Margaret A. Pericak-Vance, Ph.D.
Great Risks, Great Rewards
Dr. Margaret Pericak-Vance is Director of the Miami Institute of Human Genomics and the Dr. John T. Macdonald Foundation Professor of Human Genomics at the University of Miami Miller School of Medicine. She is a founding fellow of the American College of Medical Genetics and a board-certified Ph.D. medical geneticist. A global leader in the field of human genetics, Dr. Pericak-Vance has significantly contributed to today’s understanding of the role genomics plays in a wide range of common human diseases.
Dr. Pericak-Vance received her PhD from Indiana University in Medical Genetics. After completing her post-doctoral work at the University of North Carolina-Chapel Hill in Biostatistics, Dr. Pericak-Vance became a research investigator at the Duke University Medical Center. She remained at Duke University until 2007, where she held the title of James B. Duke Professor of Medicine and was Director of the Center for Human Genetics. In that year, she assumed leadership at the newly formed Miami Institute of Human Genomics.
Through her career, Dr. Pericak-Vance has integrated genomic and statistical technologies with a particular emphasis on neurological diseases. She has published over 400 peer-reviewed papers and established important insights in diseases that include tuberous sclerosis, the muscular dystrophies, amyotrophic lateral sclerosis (ALS), Parkinson disease (PD), multiple sclerosis (MS), autism, and Alzheimer disease (AD). In 1993, Dr. Pericak-Vance produced a groundbreaking paper in Science determining apolipoprotein E (APOE) as the major susceptibility gene for AD. Dr. Pericak-Vance has received numerous awards for her achievements in the field of medical genetics. In 2004, she was elected to the Institute of Medicine and currently holds a number of NIH research grants involving the genetics of complex diseases.